|Product||Anti-Bovine IgG monoclonal antibody|
|Reactivity||Milk, milk powder, and other biological samples|
|Source||mouse ascites, cell culture|
|Unit Size||default size is 0.5mg, custom size is available|
|Applications||ELISA, lateral flow immunoassay|
|Format||lyophilized powder or liquid|
|Purification||Purified by affinity column|
|Storage||Store at -20 degree celsius or below. Shipment at room temperature.|
|Shelf Life||12 months minimum when stored properly|
|Validated By||Internally according to ISO standards|
|Application Notes||This product is a recombinant protein for research use. Final dilution shall be determined by the end user. The product is provided in lyophilized format. We recommend to dissolve with distilled water.|
Bovine milk contains many components that have immunomodulatory and antimicrobial properties. Bovine immunoglobulins (bIg), in particular bovine IgG, have been studied since the 1970’s for their potential effects on immunity and infection in humans.
Bovine IgG can not only bind to a wide range of pathogenic bacteria and viruses, but also to many allergens. In addition, the specificity of the immunoglobulins in the milk or colostrum can be increased by vaccinating the cows before collecting their milk or colostrum. After vaccination hyperimmune colostrum is strongly enriched for IgG1 that recognizes the pathogen included in the vaccine. Indeed, the first studies on the use of oral bovine immunoglobulins to prevent and treat gastrointestinal infections have focused on the use of hyperimmune colostrum containing rotavirus-specific immunoglobulins. These were used for the treatment and prophylaxis of rotavirus infection in infants and children and showed good efficacy in several studies . Since these early studies, many studies have been performed utilizing different in vitro systems, animal models and human studies in order to determine mechanisms of action and their applicability for human health.
This Anti- Bovine IgG monoclonal antibody is a mouse monoclonal antibody produced by ascites and purified by affinity and ion-exchange, which can be used in ELISA and lateral flow assay for the detection of the target analyte.
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