Technical details
| Product | Bovine Immunoglobulin IgG ELISA Kit |
|---|---|
| Item # | E6012 |
| Principle | Competitive ELISA |
| Detection Limit | 0.05 μg/mL |
| Sample Applications | Milk, milk powder, and other biological samples |
| Package Content | Precoated microwell, 96wells Bovine IgG standard series, 6 vials, Enzyme conjugate TMB Substrate Stop solution (not available when shipping by air) Sample buffer Wash buffer |
| Storage | 2-8 ℃ in cool dark place |
| Shelf Life | 12 months when stored properly |
| Validation | Internal validation |
| Application Notes | This product is validated for milk, milk powder samples. Other sample application may be provided upon request. The product is intended for research use purpose. |
Bovine milk contains many components that have immunomodulatory and antimicrobial properties. Bovine immunoglobulins (bIg), in particular bovine IgG, have been studied since the 1970’s for their potential effects on immunity and infection in humans.
Bovine IgG can not only bind to a wide range of pathogenic bacteria and viruses, but also to many allergens. In addition, the specificity of the immunoglobulins in the milk or colostrum can be increased by vaccinating the cows before collecting their milk or colostrum. After vaccination hyperimmune colostrum is strongly enriched for IgG1 that recognizes the pathogen included in the vaccine. Indeed, the first studies on the use of oral bovine immunoglobulins to prevent and treat gastrointestinal infections have focused on the use of hyperimmune colostrum containing rotavirus-specific immunoglobulins. These were used for the treatment and prophylaxis of rotavirus infection in infants and children and showed good efficacy in several studies (described in section Treatment of Git Infection in Infants and Children and Prevention of Gastrointestinal Tract infection). Since these early studies, many studies have been performed utilizing different in vitro systems, animal models and human studies in order to determine mechanisms of action and their applicability for human health..
This product is a competitive immunoassay kit for the quantitative detection of bovine IgG in food and biological samples. This kit is validated internally and externally according to ISO standards. It is validated by more than 10 dairy factories in China.
